Consultant Clinical Scientist

Qualifications: BSc, MSc, PhD, FRCPath

Chris studied analytical chemistry at the University of Strathclyde and University of Bristol before training as a Clinical Scientist at University Hospital Wales in Cardiff. He joined the Blood Sciences department in Newcastle as a Consultant Clinical Scientist in 2013.
His specialist area of interest is in providing and developing laboratory endocrinology services and is Deputy Director of the Newcastle SAS Hormones laboratory. Assays include steroid hormones, AVP/copeptin, calcitonin, thyroglobulin, IGF-1/GH, renin/aldosterone, CgA, TRAbs, AMH and biogenic amines among others. Chris is also involved in the provision of specialist testing for lipid disorders carried out in the SAS Cardiovascular Biomarkers laboratory including beta quantification and apolipoproteins.

Recent publications:

Sahun Y, Cheetham T, Boot C, Straub V, Wood C. Using salivary testosterone measurements to assess androgen deficiency in adults with Duchenne muscular dystrophy (DMD). Endocrine Abstracts 2017;51:P016

Boot C, McFadden M, Toole B. Interference of midodrine and desglymidodrine in a plasma metanephrines LC-MS/MS assay. Endocrine Abstracts 2017;50:P184

Boot C, James RA, Tsatlidis V, Gibb F, Green F, Neely RDG. Copeptin during hypertonic saline infusion in a polyuria/polydipsia syndrome case series. Endocrine Abstracts 2017;50:P277

Hanon E, Boot C. Screening for primary aldosteronism: clinical audit of patient preparation prior to measurement of the aldosterone:renin ratio. Annals of Clinical Biochemistry 2017; 54 Suppl 1:37

Neely RDG, Boot CS. Laboratory investigation of lipoprotein X. Clinical Lipidology 2017:12;43-44

Boot C. Role of TSH receptor antibodies in the diagnosis of Graves’ disease. Clinical Laboratory International 2017, Volume 40, Dec 2016/Jan 2017 Issue, p6-8

Boot C, Toole B, Johnson S, Ball S, Neely D. Single-centre study of the diagnostic performance of plasma metanephrines with seated sampling for the diagnosis of phaeochromocytoma/paraganglioma. Annals of Clinical Biochemistry 2017;54:143-148

Boot C, Holmes E, Neely RDG. Serum non-HDL cholesterol to apolipoprotein B ratio as a screening test for familial dysbetalipoproteinaemia (Type III hyperlipidaemia) in patients with mixed hyperlipidaemia. Atherosclerosis 2016;255:7

Mackey J, Mellor A, Watchorn J, Burnett A, Boot C, Woods D. The adrenocortical response to synthetic ACTH following a trek to high altitude. Hormone and Metabolic Research 2016;48:658-663

Boot C, Armstrong L, Hughes L, Neely D. Comparison of the Neolisa and Kryptor assays for chromogranin A. Annals of Clinical Biochemistry 2016; 53 Suppl 1:34

Boot C, Banerjee P, Neely D. Assessment of the diagnostic performance of the Kryptor TSH receptor antibodies assay. Annals of Clinical Biochemistry 2016; 53 Suppl 1:33

Holmes E, Boot C, Neely D. Familial dysbetalipoproteinaemia (type III hyperlipidaemia) screening using a non-HDL-cholesterol/apo B ratio: reference range determination and comparison with apo B/total cholesterol ratio. Annals of Clinical Biochemistry 2016; 53 Suppl 1:26-27

Brown N, Gicquel J, Toole B, Boot C, Nixon L. Immunoassay screening for amphetamine and ecstasy in North of Tyne. Time for change? Annals of Clinical Biochemistry 2016; 53 Suppl 1:54

Boot C, Hughes L, Turner S, Ball S, Neely D. A comparison of plasma copeptin and AVP responses during saline infusion studies. Endocrine Abstracts 2015;38: P19

Boot C, Toole B, Johnson S, Ball S, Neely D. Single-centre audit of the diagnostic performance of plasma metanephrines with seated sampling for the diagnosis of phaeochromocytoma/paraganglioma. Endocrine Abstracts 2015;38: P31

Woods CP, Argese N, Chapman M, Boot C, Webster R, Dabhi V, Grossman AB, Toogood AA, Arlt W, Stewart PM, Crowley RK, Tomlinson JW. Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol. European Journal of Endocrinology 2015;173:633-642